Drug interactions
Ciprofloxacin + Indacaterol inhaled
Severity: Moderate
Ciprofloxacin and Indacaterol inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Indacaterol, a long-acting beta-agonist, can prolong the QTc interval at higher exposures and cause hypokalaemia. Added to ciprofloxacin it may modestly increase the risk of ventricular arrhythmia in at-risk patients.
What this interaction means in plain words
Ciprofloxacin and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation, with beta-agonist-induced hypokalaemia potentially increasing the effect.
What to do
Monitor ECG and serum potassium in patients with cardiac disease or other QT-prolonging drugs. Keep indacaterol at the labelled dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicated
- Ciprofloxacin + Fezolinetant Contraindicated
- Ciprofloxacin + Thioridazine Contraindicated
- Ciprofloxacin + Tizanidine Contraindicated
- Ciprofloxacin + Vandetanib Contraindicated
- Alosetron + Ciprofloxacin Major
Frequently asked questions
Can I take Ciprofloxacin with Indacaterol inhaled?
MediHelp rates the interaction as moderate. Ciprofloxacin and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Indacaterol, a long-acting beta-agonist, can prolong the QTc interval at higher exposures and cause hypokalaemia. Added to ciprofloxacin it may modestly increase the risk of ventricular arrhythmia in at-risk patients.
How serious is the interaction between Ciprofloxacin and Indacaterol inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium in patients with cardiac disease or other QT-prolonging drugs. Keep indacaterol at the labelled dose.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
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