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Drug interactions

Ciprofloxacin + Methyl aminolevulinate

Severity: Moderate

Ciprofloxacin and Methyl aminolevulinate: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Ciprofloxacin is phototoxic and methyl aminolevulinate is a topical photosensitizer used with light. Concurrent use could theoretically increase skin phototoxicity at the treated site, but the topical systemic exposure is low.

What this interaction means in plain words

Ciprofloxacin and Methyl aminolevulinate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive photosensitization of the skin.

What to do

Advise strict sun protection during and after treatment. Consider delaying photodynamic therapy if a course of ciprofloxacin can be completed first.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Ciprofloxacin with Methyl aminolevulinate?

MediHelp rates the interaction as moderate. Ciprofloxacin and Methyl aminolevulinate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ciprofloxacin is phototoxic and methyl aminolevulinate is a topical photosensitizer used with light. Concurrent use could theoretically increase skin phototoxicity at the treated site, but the topical systemic exposure is low.

How serious is the interaction between Ciprofloxacin and Methyl aminolevulinate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise strict sun protection during and after treatment. Consider delaying photodynamic therapy if a course of ciprofloxacin can be completed first.

What other medicines interact with Ciprofloxacin?

MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.

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