Drug interactions
Ciprofloxacin + Vilanterol / fluticasone furoate inhaled
Severity: Moderate
Ciprofloxacin and Vilanterol / fluticasone furoate inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ciprofloxacin prolongs the QT interval, and vilanterol as a beta-agonist may add to cardiovascular effects. Systemic exposure from inhalation is low, so clinical risk is generally limited but greater in patients with cardiac disease.
What this interaction means in plain words
Ciprofloxacin and Vilanterol / fluticasone furoate inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation and beta-adrenergic cardiovascular effects.
What to do
Use at labeled doses and monitor for palpitations or arrhythmia, with ECG and electrolyte checks in patients with cardiac risk factors.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicated
- Ciprofloxacin + Fezolinetant Contraindicated
- Ciprofloxacin + Thioridazine Contraindicated
- Ciprofloxacin + Tizanidine Contraindicated
- Ciprofloxacin + Vandetanib Contraindicated
- Alosetron + Ciprofloxacin Major
Frequently asked questions
Can I take Ciprofloxacin with Vilanterol / fluticasone furoate inhaled?
MediHelp rates the interaction as moderate. Ciprofloxacin and Vilanterol / fluticasone furoate inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ciprofloxacin prolongs the QT interval, and vilanterol as a beta-agonist may add to cardiovascular effects. Systemic exposure from inhalation is low, so clinical risk is generally limited but greater in patients with cardiac disease.
How serious is the interaction between Ciprofloxacin and Vilanterol / fluticasone furoate inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use at labeled doses and monitor for palpitations or arrhythmia, with ECG and electrolyte checks in patients with cardiac risk factors.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
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