Drug interactions
Cisatracurium + Lithium
Severity: Minor
Cisatracurium and Lithium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lithium has been reported to prolong the action of neuromuscular blocking agents, and this may apply to cisatracurium. The effect is generally modest but can lead to slower recovery from blockade.
What this interaction means in plain words
Cisatracurium and Lithium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cisatracurium belongs to Musculoskeletal; Lithium belongs to Central Nervous System.
Why it happens
Lithium may impair neuromuscular transmission, but the exact mechanism is not firmly established.
What to do
Use train-of-four monitoring and titrate cisatracurium to effect in patients taking lithium. Confirm full recovery before extubation.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cisatracurium
Other interactions of Lithium
- Lithium + Thioridazine Contraindicated
- Lithium + Vandetanib Contraindicated
- Aceclofenac + Lithium Major
- Acemetacin + Lithium Major
- Amisulpride + Lithium Major
- Amlodipine-benazepril + Lithium Major
Frequently asked questions
Can I take Cisatracurium with Lithium?
MediHelp rates the interaction as minor. Cisatracurium and Lithium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lithium has been reported to prolong the action of neuromuscular blocking agents, and this may apply to cisatracurium. The effect is generally modest but can lead to slower recovery from blockade.
How serious is the interaction between Cisatracurium and Lithium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use train-of-four monitoring and titrate cisatracurium to effect in patients taking lithium. Confirm full recovery before extubation.
What other medicines interact with Cisatracurium?
MediHelp also lists interactions of Cisatracurium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Benzhydrocodone / acetaminophen. The full list is on the Cisatracurium page.
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