Drug interactions
Cisatracurium + Valerian
Severity: Minor
Cisatracurium and Valerian: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Valerian has mild sedative properties, but it has no recognized effect on neuromuscular transmission, so cisatracurium paralysis is not expected to be enhanced. Any concern is limited to possible additive sedation or altered anesthetic requirements.
What this interaction means in plain words
Cisatracurium and Valerian have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible mild additive CNS depression via GABAergic activity of valerian; no effect on the neuromuscular junction is established.
What to do
No specific action is needed beyond reviewing herbal use before surgery; many centers advise stopping valerian before elective anesthesia.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cisatracurium
Frequently asked questions
Can I take Cisatracurium with Valerian?
MediHelp rates the interaction as minor. Cisatracurium and Valerian have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Valerian has mild sedative properties, but it has no recognized effect on neuromuscular transmission, so cisatracurium paralysis is not expected to be enhanced. Any concern is limited to possible additive sedation or altered anesthetic requirements.
How serious is the interaction between Cisatracurium and Valerian?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed beyond reviewing herbal use before surgery; many centers advise stopping valerian before elective anesthesia.
What other medicines interact with Cisatracurium?
MediHelp also lists interactions of Cisatracurium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Benzhydrocodone / acetaminophen. The full list is on the Cisatracurium page.
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