Drug interactions
Citalopram + Fluticasone-vilanterol
Severity: Moderate
Citalopram and Fluticasone-vilanterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Citalopram causes dose-dependent QT prolongation, and vilanterol may add tachycardia and hypokalemia. The combination may increase proarrhythmic risk in susceptible patients.
What this interaction means in plain words
Citalopram and Fluticasone-vilanterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Citalopram belongs to Central Nervous System; Fluticasone-vilanterol belongs to Respiratory.
Why it happens
Additive QT prolongation with beta-2 agonist sympathetic stimulation and hypokalemia.
What to do
Keep citalopram within the recommended maximum dose and check electrolytes. Obtain an ECG if risk factors are present or symptoms occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fluticasone-vilanterol
Other interactions of Citalopram
- Cisapride + Citalopram Contraindicated
- Citalopram + Dronedarone Contraindicated
- Citalopram + Escitalopram Contraindicated
- Citalopram + Isocarboxazid Contraindicated
- Citalopram + Methylene blue Contraindicated
- Citalopram + Phenelzine Contraindicated
Frequently asked questions
Can I take Citalopram with Fluticasone-vilanterol?
MediHelp rates the interaction as moderate. Citalopram and Fluticasone-vilanterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Citalopram causes dose-dependent QT prolongation, and vilanterol may add tachycardia and hypokalemia. The combination may increase proarrhythmic risk in susceptible patients.
How serious is the interaction between Citalopram and Fluticasone-vilanterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Keep citalopram within the recommended maximum dose and check electrolytes. Obtain an ECG if risk factors are present or symptoms occur.
What other medicines interact with Fluticasone-vilanterol?
MediHelp also lists interactions of Fluticasone-vilanterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Fluticasone-vilanterol page.
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