Drug interactions
cobicistat + triazolam
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
↑ triazolam → respiratory depression; contraindicated.
Mechanism of action
Strong CYP3A4 inhibition.
Clinical management
Contraindicated.
References
Frequently asked questions
Can I take cobicistat with triazolam?
The interaction is rated: Contraindicated. ↑ triazolam → respiratory depression; contraindicated.
How serious is the interaction between cobicistat and triazolam?
The interaction is rated: Contraindicated. Evidence level: High.
How is the interaction between cobicistat and triazolam managed?
Contraindicated.
Why do cobicistat and triazolam interact?
Strong CYP3A4 inhibition.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.