Drug interactions
Coenzyme q10 + Tolazamide
Severity: Minor
Coenzyme q10 and Tolazamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sulfonylureas may lower coenzyme Q10 levels, but the clinical importance is unclear. Coenzyme Q10 has also been reported to have mild glucose-lowering effects.
What this interaction means in plain words
Coenzyme q10 and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
The mechanism is not established.
What to do
No routine action is needed. Monitor blood glucose if coenzyme Q10 supplementation is started.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolazamide
- Disopyramide + Tolazamide Major
- Insulin degludec-liraglutide + Tolazamide Major
- Aceclofenac + Tolazamide Moderate
- Acemetacin + Tolazamide Moderate
- Acetylsalicylic acid + Tolazamide Moderate
- Albiglutide + Tolazamide Moderate
Frequently asked questions
Can I take Coenzyme q10 with Tolazamide?
MediHelp rates the interaction as minor. Coenzyme q10 and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sulfonylureas may lower coenzyme Q10 levels, but the clinical importance is unclear. Coenzyme Q10 has also been reported to have mild glucose-lowering effects.
How serious is the interaction between Coenzyme q10 and Tolazamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Monitor blood glucose if coenzyme Q10 supplementation is started.
What other medicines interact with Tolazamide?
MediHelp also lists interactions of Tolazamide with, for example, Disopyramide, Insulin degludec-liraglutide, Aceclofenac. The full list is on the Tolazamide page.
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