Drug interactions
Colestipol + Dexamethasone-tobramycin
Severity: Minor
Colestipol and Dexamethasone-tobramycin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Colestipol is a bile acid sequestrant that can bind oral drugs in the gut and reduce their absorption. Oral dexamethasone absorption may fall, weakening its effect. Ophthalmic dexamethasone is not affected.
What this interaction means in plain words
Colestipol and Dexamethasone-tobramycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Colestipol belongs to Cardiovascular; Dexamethasone-tobramycin belongs to Anti Bacterial.
Why it happens
Binding of dexamethasone by colestipol in the gastrointestinal tract, reducing absorption.
What to do
If oral dexamethasone is used, give it at least 1 hour before or 4 hours after colestipol. No action is needed for ophthalmic use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dexamethasone-tobramycin
Other interactions of Colestipol
- Amlodipine-hydrochlorothiazide-valsartan + Colestipol Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Colestipol Moderate
- Atenolol-chlorthalidone + Colestipol Moderate
- Azilsartan-chlorthalidone + Colestipol Moderate
- Candesartan-hydrochlorothiazide + Colestipol Moderate
- Captopril-hydrochlorothiazide + Colestipol Moderate
Frequently asked questions
Can I take Colestipol with Dexamethasone-tobramycin?
MediHelp rates the interaction as minor. Colestipol and Dexamethasone-tobramycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Colestipol is a bile acid sequestrant that can bind oral drugs in the gut and reduce their absorption. Oral dexamethasone absorption may fall, weakening its effect. Ophthalmic dexamethasone is not affected.
How serious is the interaction between Colestipol and Dexamethasone-tobramycin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: If oral dexamethasone is used, give it at least 1 hour before or 4 hours after colestipol. No action is needed for ophthalmic use.
What other medicines interact with Dexamethasone-tobramycin?
MediHelp also lists interactions of Dexamethasone-tobramycin with, for example, Capreomycin, Carboplatin, Ciprofloxacin. The full list is on the Dexamethasone-tobramycin page.
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