Drug interactions
Colestipol + Vitamin b3
Severity: Moderate
Colestipol and Vitamin b3: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Colestipol, a bile acid sequestrant, can bind niacin in the gut and reduce its absorption when taken at the same time. This may lessen the lipid-lowering effect of niacin. The two are often combined deliberately for lipid control, so timing matters.
What this interaction means in plain words
Colestipol and Vitamin b3 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Colestipol belongs to Cardiovascular; Vitamin b3 belongs to Gastrointestinal Tract.
Why it happens
Colestipol binds niacin in the gastrointestinal tract, decreasing its absorption.
What to do
Give niacin at least 1 hour before or 4 to 6 hours after colestipol. Monitor lipid response and adjust doses as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Vitamin b3
- Lovastatin + Vitamin b3 Major
- Simvastatin + Vitamin b3 Major
- Atorvastatin + Vitamin b3 Moderate
- Cholestyramine + Vitamin b3 Moderate
- Fluvastatin + Vitamin b3 Moderate
- Insulin aspart protamine / insulin aspart + Vitamin b3 Moderate
Other interactions of Colestipol
- Amlodipine-hydrochlorothiazide-valsartan + Colestipol Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Colestipol Moderate
- Atenolol-chlorthalidone + Colestipol Moderate
- Azilsartan-chlorthalidone + Colestipol Moderate
- Candesartan-hydrochlorothiazide + Colestipol Moderate
- Captopril-hydrochlorothiazide + Colestipol Moderate
Frequently asked questions
Can I take Colestipol with Vitamin b3?
MediHelp rates the interaction as moderate. Colestipol and Vitamin b3 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colestipol, a bile acid sequestrant, can bind niacin in the gut and reduce its absorption when taken at the same time. This may lessen the lipid-lowering effect of niacin. The two are often combined deliberately for lipid control, so timing matters.
How serious is the interaction between Colestipol and Vitamin b3?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give niacin at least 1 hour before or 4 to 6 hours after colestipol. Monitor lipid response and adjust doses as needed.
What other medicines interact with Vitamin b3?
MediHelp also lists interactions of Vitamin b3 with, for example, Lovastatin, Simvastatin, Atorvastatin. The full list is on the Vitamin b3 page.
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