Drug interactions
Copper + Sarecycline
Severity: Moderate
Copper and Sarecycline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral copper supplements may chelate sarecycline in the gut and reduce its absorption, potentially reducing efficacy.
What this interaction means in plain words
Copper and Sarecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Copper belongs to Gastrointestinal Tract; Sarecycline belongs to Anti Bacterial.
Why it happens
Chelation of the tetracycline by polyvalent metal cations in the gastrointestinal tract reduces absorption.
What to do
Separate sarecycline from copper-containing supplements by at least 2 to 3 hours, or avoid the supplement during therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Copper
- Copper + Omadacycline Moderate
- Copper + Penicillamine Moderate
- Copper + Trientine Moderate
- Ascorbic acid + Copper Minor
- Baloxavir marboxil + Copper Minor
- Copper + Vitamin c Minor
Other interactions of Sarecycline
- Acitretin + Sarecycline Contraindicated
- Isotretinoin + Sarecycline Major
- Sarecycline + Tretinoin Major
- Aluminum hydroxide + Sarecycline Moderate
- Calcium carbonate + Sarecycline Moderate
- Calcium + Sarecycline Moderate
Frequently asked questions
Can I take Copper with Sarecycline?
MediHelp rates the interaction as moderate. Copper and Sarecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral copper supplements may chelate sarecycline in the gut and reduce its absorption, potentially reducing efficacy.
How serious is the interaction between Copper and Sarecycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate sarecycline from copper-containing supplements by at least 2 to 3 hours, or avoid the supplement during therapy.
What other medicines interact with Copper?
MediHelp also lists interactions of Copper with, for example, Omadacycline, Penicillamine, Trientine. The full list is on the Copper page.
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