Drug interactions
Cordyceps + Indomethacin
Severity: Minor
Cordyceps and Indomethacin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cordyceps has been reported to have antiplatelet properties in preclinical data, so it could theoretically add to the bleeding risk of indomethacin. Clinical evidence is scarce.
What this interaction means in plain words
Cordyceps and Indomethacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive antiplatelet effect; not well characterized in humans.
What to do
Ask patients about supplement use and advise reporting bruising or bleeding. Consider stopping the supplement if bleeding occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Indomethacin
- Indomethacin + Ketorolac Contraindicated
- Indomethacin + Ketorolac intranasal Contraindicated
- Aceclofenac + Indomethacin Major
- Acemetacin + Indomethacin Major
- Acetylsalicylic acid + Indomethacin Major
- Alteplase + Indomethacin Major
Frequently asked questions
Can I take Cordyceps with Indomethacin?
MediHelp rates the interaction as minor. Cordyceps and Indomethacin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cordyceps has been reported to have antiplatelet properties in preclinical data, so it could theoretically add to the bleeding risk of indomethacin. Clinical evidence is scarce.
How serious is the interaction between Cordyceps and Indomethacin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about supplement use and advise reporting bruising or bleeding. Consider stopping the supplement if bleeding occurs.
What other medicines interact with Indomethacin?
MediHelp also lists interactions of Indomethacin with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Indomethacin page.
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