Drug interactions
Cornsilk + Enalapril-hydrochlorothiazide
Severity: Minor
Cornsilk and Enalapril-hydrochlorothiazide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cornsilk has mild diuretic and potassium-lowering properties reported in traditional use. Taken with a thiazide it could add to potassium and fluid loss, although clinical data are scarce.
What this interaction means in plain words
Cornsilk and Enalapril-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive diuretic and kaliuretic effect; not well characterized.
What to do
Advise patients to avoid cornsilk supplements while on thiazide therapy, or monitor serum potassium and blood pressure if used. The ACE inhibitor component partly offsets potassium loss.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Enalapril-hydrochlorothiazide
- Aliskiren + Enalapril-hydrochlorothiazide Contraindicated
- Dofetilide + Enalapril-hydrochlorothiazide Contraindicated
- Enalapril-hydrochlorothiazide + Protein a column Contraindicated
- Enalapril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Amifostine + Enalapril-hydrochlorothiazide Major
- Amiloride + Enalapril-hydrochlorothiazide Major
Frequently asked questions
Can I take Cornsilk with Enalapril-hydrochlorothiazide?
MediHelp rates the interaction as minor. Cornsilk and Enalapril-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cornsilk has mild diuretic and potassium-lowering properties reported in traditional use. Taken with a thiazide it could add to potassium and fluid loss, although clinical data are scarce.
How serious is the interaction between Cornsilk and Enalapril-hydrochlorothiazide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid cornsilk supplements while on thiazide therapy, or monitor serum potassium and blood pressure if used. The ACE inhibitor component partly offsets potassium loss.
What other medicines interact with Enalapril-hydrochlorothiazide?
MediHelp also lists interactions of Enalapril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Protein a column. The full list is on the Enalapril-hydrochlorothiazide page.
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