Drug interactions
Cornsilk + Tolazamide
Severity: Minor
Cornsilk and Tolazamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cornsilk has reported glucose-lowering properties in animal studies, so it could theoretically add to tolazamide and raise hypoglycemia risk. Human data are lacking.
What this interaction means in plain words
Cornsilk and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive hypoglycemic effect; the mechanism is unestablished.
What to do
Monitor blood glucose if cornsilk is used regularly. Reduce the tolazamide dose only if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tolazamide
- Disopyramide + Tolazamide Major
- Insulin degludec-liraglutide + Tolazamide Major
- Aceclofenac + Tolazamide Moderate
- Acemetacin + Tolazamide Moderate
- Acetylsalicylic acid + Tolazamide Moderate
- Albiglutide + Tolazamide Moderate
Frequently asked questions
Can I take Cornsilk with Tolazamide?
MediHelp rates the interaction as minor. Cornsilk and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cornsilk has reported glucose-lowering properties in animal studies, so it could theoretically add to tolazamide and raise hypoglycemia risk. Human data are lacking.
How serious is the interaction between Cornsilk and Tolazamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose if cornsilk is used regularly. Reduce the tolazamide dose only if hypoglycemia occurs.
What other medicines interact with Tolazamide?
MediHelp also lists interactions of Tolazamide with, for example, Disopyramide, Insulin degludec-liraglutide, Aceclofenac. The full list is on the Tolazamide page.
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