Drug interactions
Cortisone + Felodipine
Severity: Minor
Cortisone and Felodipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids may weakly induce CYP3A4, potentially lowering felodipine levels, though this is minor with cortisone. Sodium and fluid retention from corticosteroids may also oppose antihypertensive effect.
What this interaction means in plain words
Cortisone and Felodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible mild CYP3A4 induction plus mineralocorticoid-related fluid retention.
What to do
Monitor blood pressure during prolonged corticosteroid therapy and adjust felodipine if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Felodipine
- Felodipine + Itraconazole Contraindicated
- Aldesleukin + Felodipine Major
- Amifostine + Felodipine Major
- Apalutamide + Felodipine Major
- Atazanavir + Felodipine Major
- Carbamazepine + Felodipine Major
Frequently asked questions
Can I take Cortisone with Felodipine?
MediHelp rates the interaction as minor. Cortisone and Felodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids may weakly induce CYP3A4, potentially lowering felodipine levels, though this is minor with cortisone. Sodium and fluid retention from corticosteroids may also oppose antihypertensive effect.
How serious is the interaction between Cortisone and Felodipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure during prolonged corticosteroid therapy and adjust felodipine if control worsens.
What other medicines interact with Felodipine?
MediHelp also lists interactions of Felodipine with, for example, Itraconazole, Aldesleukin, Amifostine. The full list is on the Felodipine page.
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