Drug interactions
Cortisone + Nimodipine
Severity: Minor
Cortisone and Nimodipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids may weakly induce CYP3A4, which could modestly lower nimodipine levels. The clinical effect is generally small.
What this interaction means in plain words
Cortisone and Nimodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Weak glucocorticoid-mediated CYP3A4 induction increases nimodipine metabolism.
What to do
No routine dose change is required. Monitor therapeutic response if high-dose or prolonged steroid therapy is given.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nimodipine
- Apalutamide + Nimodipine Major
- Carbamazepine + Nimodipine Major
- Ceritinib + Nimodipine Major
- Clarithromycin + Nimodipine Major
- Cobicistat + Nimodipine Major
- Darunavir + Nimodipine Major
Frequently asked questions
Can I take Cortisone with Nimodipine?
MediHelp rates the interaction as minor. Cortisone and Nimodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids may weakly induce CYP3A4, which could modestly lower nimodipine levels. The clinical effect is generally small.
How serious is the interaction between Cortisone and Nimodipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is required. Monitor therapeutic response if high-dose or prolonged steroid therapy is given.
What other medicines interact with Nimodipine?
MediHelp also lists interactions of Nimodipine with, for example, Apalutamide, Carbamazepine, Ceritinib. The full list is on the Nimodipine page.
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