Drug interactions
Cyclizine + Scullcap
Severity: Minor
Cyclizine and Scullcap: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Skullcap is used as a herbal sedative and might add to the drowsiness caused by cyclizine. Evidence is limited and largely theoretical.
What this interaction means in plain words
Cyclizine and Scullcap have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive CNS depression; the herb's sedative mechanism is not well established.
What to do
Advise patients to watch for increased drowsiness and avoid driving if affected. Stop the herb if sedation is excessive.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cyclizine
- Calcium / magnesium / potassium / sodium oxybates + Cyclizine Major
- Cyclizine + Henbane Major
- Cyclizine + Sodium oxybate Major
- Abobotulinumtoxina + Cyclizine Moderate
- Alfentanil + Cyclizine Moderate
- Alprazolam + Cyclizine Moderate
Frequently asked questions
Can I take Cyclizine with Scullcap?
MediHelp rates the interaction as minor. Cyclizine and Scullcap have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Skullcap is used as a herbal sedative and might add to the drowsiness caused by cyclizine. Evidence is limited and largely theoretical.
How serious is the interaction between Cyclizine and Scullcap?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to watch for increased drowsiness and avoid driving if affected. Stop the herb if sedation is excessive.
What other medicines interact with Cyclizine?
MediHelp also lists interactions of Cyclizine with, for example, Calcium / magnesium / potassium / sodium oxybates, Henbane, Sodium oxybate. The full list is on the Cyclizine page.
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