Drug interactions
Cyclopenthiazide + Formoterol-mometasone
Severity: Moderate
Cyclopenthiazide and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cyclopenthiazide, a thiazide diuretic, causes renal potassium loss, and formoterol can further lower serum potassium by cellular uptake. Combined hypokalemia may increase the risk of arrhythmias, particularly in patients with cardiac disease.
What this interaction means in plain words
Cyclopenthiazide and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypokalemia from renal potassium wasting and beta-2 agonist-driven intracellular potassium shift.
What to do
Monitor serum potassium, particularly at initiation and during acute respiratory illness, and replace potassium as required.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Frequently asked questions
Can I take Cyclopenthiazide with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Cyclopenthiazide and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cyclopenthiazide, a thiazide diuretic, causes renal potassium loss, and formoterol can further lower serum potassium by cellular uptake. Combined hypokalemia may increase the risk of arrhythmias, particularly in patients with cardiac disease.
How serious is the interaction between Cyclopenthiazide and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium, particularly at initiation and during acute respiratory illness, and replace potassium as required.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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