Drug interactions
Cyclosporin + Fesoterodine
Severity: Minor
Cyclosporin and Fesoterodine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cyclosporin may modestly increase exposure to fesoterodine's active metabolite, intensifying anticholinergic effects such as dry mouth and constipation. The effect is usually small with weak to moderate CYP3A4 inhibitors.
What this interaction means in plain words
Cyclosporin and Fesoterodine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cyclosporin belongs to Miscellaneous; Fesoterodine belongs to Genitourinary.
Why it happens
Cyclosporin inhibits CYP3A4, a secondary pathway for fesoterodine's active metabolite.
What to do
No dose change is usually needed; monitor for anticholinergic adverse effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cyclosporin
- Adenovirus types 4 and 7 live + Cyclosporin Contraindicated
- Aliskiren + Cyclosporin Contraindicated
- Bcg vaccine live + Cyclosporin Contraindicated
- Bosentan + Cyclosporin Contraindicated
- Cidofovir + Cyclosporin Contraindicated
- Cyclosporin + Dengue vaccine Contraindicated
Other interactions of Fesoterodine
Frequently asked questions
Can I take Cyclosporin with Fesoterodine?
MediHelp rates the interaction as minor. Cyclosporin and Fesoterodine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cyclosporin may modestly increase exposure to fesoterodine's active metabolite, intensifying anticholinergic effects such as dry mouth and constipation. The effect is usually small with weak to moderate CYP3A4 inhibitors.
How serious is the interaction between Cyclosporin and Fesoterodine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed; monitor for anticholinergic adverse effects.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
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