Drug interactions
Dabigatran etexilate + Fish oil
Severity: Minor
Dabigatran etexilate and Fish oil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
High doses of fish oil have mild antiplatelet effects and may slightly raise bleeding tendency in people on anticoagulants. At usual supplement doses the effect is small and clinically significant bleeding is uncommon.
What this interaction means in plain words
Dabigatran etexilate and Fish oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dabigatran etexilate belongs to Cardiovascular; Fish oil belongs to Gastrointestinal Tract.
Why it happens
Omega-3 fatty acids modestly reduce platelet aggregation, adding to the anticoagulant effect.
What to do
No dose change is needed at usual doses. Advise patients to report unusual bleeding or bruising, especially with high-dose supplements.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dabigatran etexilate
- Dabigatran etexilate + Defibrotide Contraindicated
- Dabigatran etexilate + Ketorolac Contraindicated
- Dabigatran etexilate + Mifepristone Contraindicated
- Abciximab + Dabigatran etexilate Major
- Alteplase + Dabigatran etexilate Major
- Amiodarone + Dabigatran etexilate Major
Other interactions of Fish oil
- Antithrombin alfa + Fish oil Moderate
- Antithrombin iii + Fish oil Moderate
- Aspirin / citric acid / sodium bicarbonate + Fish oil Moderate
- Aspirin + Fish oil Moderate
- Betrixaban + Fish oil Moderate
- Bivalirudin + Fish oil Moderate
Frequently asked questions
Can I take Dabigatran etexilate with Fish oil?
MediHelp rates the interaction as minor. Dabigatran etexilate and Fish oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. High doses of fish oil have mild antiplatelet effects and may slightly raise bleeding tendency in people on anticoagulants. At usual supplement doses the effect is small and clinically significant bleeding is uncommon.
How serious is the interaction between Dabigatran etexilate and Fish oil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed at usual doses. Advise patients to report unusual bleeding or bruising, especially with high-dose supplements.
What other medicines interact with Dabigatran etexilate?
MediHelp also lists interactions of Dabigatran etexilate with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dabigatran etexilate page.
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