Drug interactions
Dabigatran etexilate + Suvorexant
Severity: Minor
Dabigatran etexilate and Suvorexant: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Suvorexant may weakly inhibit P-glycoprotein, and any increase in dabigatran exposure is expected to be small.
What this interaction means in plain words
Dabigatran etexilate and Suvorexant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dabigatran etexilate belongs to Cardiovascular; Suvorexant belongs to Central Nervous System.
Why it happens
Weak P-glycoprotein inhibition by suvorexant may slightly increase dabigatran etexilate absorption.
What to do
No dose adjustment is usually needed; monitor for bleeding in patients with renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dabigatran etexilate
- Dabigatran etexilate + Defibrotide Contraindicated
- Dabigatran etexilate + Ketorolac Contraindicated
- Dabigatran etexilate + Mifepristone Contraindicated
- Abciximab + Dabigatran etexilate Major
- Alteplase + Dabigatran etexilate Major
- Amiodarone + Dabigatran etexilate Major
Other interactions of Suvorexant
Frequently asked questions
Can I take Dabigatran etexilate with Suvorexant?
MediHelp rates the interaction as minor. Dabigatran etexilate and Suvorexant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Suvorexant may weakly inhibit P-glycoprotein, and any increase in dabigatran exposure is expected to be small.
How serious is the interaction between Dabigatran etexilate and Suvorexant?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is usually needed; monitor for bleeding in patients with renal impairment.
What other medicines interact with Dabigatran etexilate?
MediHelp also lists interactions of Dabigatran etexilate with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dabigatran etexilate page.
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