Drug interactions
Dabrafenib + Dutasteride-tamsulosin
Severity: Minor
Dabrafenib and Dutasteride-tamsulosin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dabrafenib is a CYP3A4 inducer and can lower exposure to tamsulosin and dutasteride. The result may be reduced control of urinary symptoms.
What this interaction means in plain words
Dabrafenib and Dutasteride-tamsulosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dabrafenib belongs to Oncology; Dutasteride-tamsulosin belongs to Genitourinary.
Why it happens
Induction of CYP3A4 by dabrafenib increases metabolic clearance of tamsulosin and dutasteride.
What to do
Monitor for loss of symptom relief while on dabrafenib. Adjust therapy if efficacy is lost.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Dabrafenib and Dutasteride-tamsulosin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Dutasteride-tamsulosin
Other interactions of Dabrafenib
Frequently asked questions
Can I take Dabrafenib with Dutasteride-tamsulosin?
MediHelp rates the interaction as minor. Dabrafenib and Dutasteride-tamsulosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dabrafenib is a CYP3A4 inducer and can lower exposure to tamsulosin and dutasteride. The result may be reduced control of urinary symptoms.
How serious is the interaction between Dabrafenib and Dutasteride-tamsulosin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for loss of symptom relief while on dabrafenib. Adjust therapy if efficacy is lost.
What other medicines interact with Dutasteride-tamsulosin?
MediHelp also lists interactions of Dutasteride-tamsulosin with, for example, Alfuzosin, Amifostine, Atazanavir. The full list is on the Dutasteride-tamsulosin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
