Drug interactions
Damiana + Tolazamide
Severity: Minor
Damiana and Tolazamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Damiana has been reported to have glucose-lowering activity in animal studies, so an additive effect with tolazamide is theoretical. The legacy suggestion of reduced efficacy is not supported by clear evidence.
What this interaction means in plain words
Damiana and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical pharmacodynamic effect on glucose; the mechanism is not established.
What to do
Monitor blood glucose if damiana is used regularly. Adjust the tolazamide dose only if glycemic changes occur.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Damiana and Tolazamide, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Tolazamide
- Disopyramide + Tolazamide Major
- Insulin degludec-liraglutide + Tolazamide Major
- Aceclofenac + Tolazamide Moderate
- Acemetacin + Tolazamide Moderate
- Acetylsalicylic acid + Tolazamide Moderate
- Albiglutide + Tolazamide Moderate
Frequently asked questions
Can I take Damiana with Tolazamide?
MediHelp rates the interaction as minor. Damiana and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Damiana has been reported to have glucose-lowering activity in animal studies, so an additive effect with tolazamide is theoretical. The legacy suggestion of reduced efficacy is not supported by clear evidence.
How serious is the interaction between Damiana and Tolazamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose if damiana is used regularly. Adjust the tolazamide dose only if glycemic changes occur.
What other medicines interact with Tolazamide?
MediHelp also lists interactions of Tolazamide with, for example, Disopyramide, Insulin degludec-liraglutide, Aceclofenac. The full list is on the Tolazamide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
