Drug interactions
Danazol + Prednisone
Severity: Minor
Danazol and Prednisone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause fluid retention and edema, so the combination may worsen swelling. Danazol may also modestly raise corticosteroid exposure.
What this interaction means in plain words
Danazol and Prednisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive sodium and fluid retention, with possible danazol inhibition of corticosteroid metabolism.
What to do
Monitor weight, blood pressure and edema, and reduce the steroid dose if fluid retention develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Prednisone
- Bcg vaccine live + Prednisone Contraindicated
- Measles vaccine + Prednisone Contraindicated
- Mifepristone + Prednisone Contraindicated
- Prednisone + Radium-223 dichloride Contraindicated
- Prednisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Prednisone Major
Frequently asked questions
Can I take Danazol with Prednisone?
MediHelp rates the interaction as minor. Danazol and Prednisone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs can cause fluid retention and edema, so the combination may worsen swelling. Danazol may also modestly raise corticosteroid exposure.
How serious is the interaction between Danazol and Prednisone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor weight, blood pressure and edema, and reduce the steroid dose if fluid retention develops.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Measles vaccine, Mifepristone. The full list is on the Prednisone page.
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