Drug interactions
Danazol + Umeclidinium-vilanterol
Severity: Minor
Danazol and Umeclidinium-vilanterol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Danazol weakly inhibits CYP3A4 and may slightly increase vilanterol exposure. Clinical significance is likely small.
What this interaction means in plain words
Danazol and Umeclidinium-vilanterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Danazol weakly inhibits CYP3A4-mediated vilanterol metabolism.
What to do
No dose adjustment is usually needed; watch for palpitations or tremor.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Umeclidinium-vilanterol
Frequently asked questions
Can I take Danazol with Umeclidinium-vilanterol?
MediHelp rates the interaction as minor. Danazol and Umeclidinium-vilanterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Danazol weakly inhibits CYP3A4 and may slightly increase vilanterol exposure. Clinical significance is likely small.
How serious is the interaction between Danazol and Umeclidinium-vilanterol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is usually needed; watch for palpitations or tremor.
What other medicines interact with Umeclidinium-vilanterol?
MediHelp also lists interactions of Umeclidinium-vilanterol with, for example, Aclidinium, Amiodarone, Amitriptyline. The full list is on the Umeclidinium-vilanterol page.
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