Drug interactions
Dapagliflozin-metformin + Diethylpropion
Severity: Minor
Dapagliflozin-metformin and Diethylpropion: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Diethylpropion, an anorectic sympathomimetic, can alter glycemia through weight loss and changes in appetite and insulin requirements. Control may shift in either direction.
What this interaction means in plain words
Dapagliflozin-metformin and Diethylpropion have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
The sympathomimetic effects and the changes in intake and weight alter glucose levels. A direct interaction is not well established.
What to do
Monitor blood glucose when diethylpropion is started or stopped. Reduce antidiabetic doses if hypoglycemia occurs with weight loss.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dapagliflozin-metformin
Frequently asked questions
Can I take Dapagliflozin-metformin with Diethylpropion?
MediHelp rates the interaction as minor. Dapagliflozin-metformin and Diethylpropion have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Diethylpropion, an anorectic sympathomimetic, can alter glycemia through weight loss and changes in appetite and insulin requirements. Control may shift in either direction.
How serious is the interaction between Dapagliflozin-metformin and Diethylpropion?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when diethylpropion is started or stopped. Reduce antidiabetic doses if hypoglycemia occurs with weight loss.
What other medicines interact with Dapagliflozin-metformin?
MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Dapagliflozin-metformin page.
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