Drug interactions
Dapagliflozin-metformin + Ethinylestradiol
Severity: Minor
Dapagliflozin-metformin and Ethinylestradiol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ethinylestradiol, particularly in combined contraceptives, can modestly reduce glucose tolerance and may weaken glycemic control. The effect is usually small.
What this interaction means in plain words
Dapagliflozin-metformin and Ethinylestradiol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Estrogens can alter insulin sensitivity, giving a pharmacodynamic opposition to the antidiabetic drugs.
What to do
Monitor blood glucose when starting or stopping estrogen-containing products. Adjust antidiabetic therapy if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dapagliflozin-metformin
Frequently asked questions
Can I take Dapagliflozin-metformin with Ethinylestradiol?
MediHelp rates the interaction as minor. Dapagliflozin-metformin and Ethinylestradiol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ethinylestradiol, particularly in combined contraceptives, can modestly reduce glucose tolerance and may weaken glycemic control. The effect is usually small.
How serious is the interaction between Dapagliflozin-metformin and Ethinylestradiol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping estrogen-containing products. Adjust antidiabetic therapy if needed.
What other medicines interact with Dapagliflozin-metformin?
MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Dapagliflozin-metformin page.
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