Drug interactions
Dapagliflozin-metformin + Fluoxymesterone
Severity: Minor
Dapagliflozin-metformin and Fluoxymesterone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgenic anabolic steroids such as fluoxymesterone may improve insulin sensitivity and lower blood glucose in some patients. Combined with glucose-lowering drugs this may modestly increase the glucose-lowering effect. The risk of clinically important hypoglycemia with metformin and dapagliflozin is low.
What this interaction means in plain words
Dapagliflozin-metformin and Fluoxymesterone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Androgens may enhance insulin sensitivity, producing an additive glucose-lowering effect.
What to do
Monitor blood glucose when starting or stopping fluoxymesterone and adjust antidiabetic therapy only if glucose changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dapagliflozin-metformin
Frequently asked questions
Can I take Dapagliflozin-metformin with Fluoxymesterone?
MediHelp rates the interaction as minor. Dapagliflozin-metformin and Fluoxymesterone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Androgenic anabolic steroids such as fluoxymesterone may improve insulin sensitivity and lower blood glucose in some patients. Combined with glucose-lowering drugs this may modestly increase the glucose-lowering effect. The risk of clinically important hypoglycemia with metformin and dapagliflozin is low.
How serious is the interaction between Dapagliflozin-metformin and Fluoxymesterone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping fluoxymesterone and adjust antidiabetic therapy only if glucose changes.
What other medicines interact with Dapagliflozin-metformin?
MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Dapagliflozin-metformin page.
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