Drug interactions
Dapagliflozin-metformin + Glucagon intranasal
Severity: Minor
Dapagliflozin-metformin and Glucagon intranasal: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glucagon raises blood glucose and directly opposes the effects of antidiabetic drugs. This is the intended use in hypoglycemia, and the effect is short-lived.
What this interaction means in plain words
Dapagliflozin-metformin and Glucagon intranasal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Glucagon stimulates hepatic glycogenolysis and gluconeogenesis, counteracting glucose-lowering drugs.
What to do
No dose change is needed for emergency use. Monitor blood glucose after use and treat the cause of the hypoglycemia.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dapagliflozin-metformin
Frequently asked questions
Can I take Dapagliflozin-metformin with Glucagon intranasal?
MediHelp rates the interaction as minor. Dapagliflozin-metformin and Glucagon intranasal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Glucagon raises blood glucose and directly opposes the effects of antidiabetic drugs. This is the intended use in hypoglycemia, and the effect is short-lived.
How serious is the interaction between Dapagliflozin-metformin and Glucagon intranasal?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed for emergency use. Monitor blood glucose after use and treat the cause of the hypoglycemia.
What other medicines interact with Dapagliflozin-metformin?
MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Dapagliflozin-metformin page.
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