Drug interactions
Dapagliflozin-metformin + Isradipine
Severity: Minor
Dapagliflozin-metformin and Isradipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dihydropyridine calcium channel blockers such as isradipine can occasionally impair glucose tolerance and modestly reduce the effect of antidiabetic drugs. The effect is usually small and clinically minor.
What this interaction means in plain words
Dapagliflozin-metformin and Isradipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Calcium channel blockade may slightly reduce insulin secretion and tissue glucose handling.
What to do
Check glucose control routinely after starting or stopping isradipine and adjust antidiabetic therapy only if control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dapagliflozin-metformin
Frequently asked questions
Can I take Dapagliflozin-metformin with Isradipine?
MediHelp rates the interaction as minor. Dapagliflozin-metformin and Isradipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dihydropyridine calcium channel blockers such as isradipine can occasionally impair glucose tolerance and modestly reduce the effect of antidiabetic drugs. The effect is usually small and clinically minor.
How serious is the interaction between Dapagliflozin-metformin and Isradipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check glucose control routinely after starting or stopping isradipine and adjust antidiabetic therapy only if control changes.
What other medicines interact with Dapagliflozin-metformin?
MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Dapagliflozin-metformin page.
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