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Drug interactions

Dapagliflozin-metformin + Phendimetrazine

Severity: Minor

Dapagliflozin-metformin and Phendimetrazine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Phendimetrazine is an anorectic sympathomimetic that may alter glucose requirements, and weight loss often lowers antidiabetic needs. The net effect on control is variable.

What this interaction means in plain words

Dapagliflozin-metformin and Phendimetrazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Sympathomimetic effects and reduced food intake alter glycemic control.

What to do

Monitor glucose when starting or stopping phendimetrazine and adjust antidiabetic doses as needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Dapagliflozin-metformin with Phendimetrazine?

MediHelp rates the interaction as minor. Dapagliflozin-metformin and Phendimetrazine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Phendimetrazine is an anorectic sympathomimetic that may alter glucose requirements, and weight loss often lowers antidiabetic needs. The net effect on control is variable.

How serious is the interaction between Dapagliflozin-metformin and Phendimetrazine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose when starting or stopping phendimetrazine and adjust antidiabetic doses as needed.

What other medicines interact with Dapagliflozin-metformin?

MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Dapagliflozin-metformin page.

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