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Drug interactions

Dapagliflozin-metformin + Shark cartilage

Severity: Minor

Dapagliflozin-metformin and Shark cartilage: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Shark cartilage has been suggested to affect blood glucose, and an additive hypoglycemic effect with antidiabetic drugs is theoretical. Clinical data are scarce and product composition is variable.

What this interaction means in plain words

Dapagliflozin-metformin and Shark cartilage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

A possible additive glucose-lowering effect has been proposed but is not established.

What to do

Advise patients to report use of the supplement and monitor blood glucose if it is taken regularly.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Dapagliflozin-metformin with Shark cartilage?

MediHelp rates the interaction as minor. Dapagliflozin-metformin and Shark cartilage have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Shark cartilage has been suggested to affect blood glucose, and an additive hypoglycemic effect with antidiabetic drugs is theoretical. Clinical data are scarce and product composition is variable.

How serious is the interaction between Dapagliflozin-metformin and Shark cartilage?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report use of the supplement and monitor blood glucose if it is taken regularly.

What other medicines interact with Dapagliflozin-metformin?

MediHelp also lists interactions of Dapagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Dapagliflozin-metformin page.

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