Drug interactions
Deferasirox + Prednisone
Severity: Moderate
Deferasirox and Prednisone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can injure the gastrointestinal mucosa, and deferasirox carries labeled warnings for GI hemorrhage and ulceration. Concurrent corticosteroid use may add to this risk, particularly in older patients or those with advanced disease and low platelets.
What this interaction means in plain words
Deferasirox and Prednisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deferasirox belongs to Miscellaneous; Prednisone belongs to Endocrine.
Why it happens
Additive gastrointestinal mucosal toxicity and bleeding risk.
What to do
Monitor for GI symptoms and bleeding and consider gastroprotection in at-risk patients. Promptly evaluate any GI bleeding and interrupt deferasirox if it occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Prednisone
- Bcg vaccine live + Prednisone Contraindicated
- Measles vaccine + Prednisone Contraindicated
- Mifepristone + Prednisone Contraindicated
- Prednisone + Radium-223 dichloride Contraindicated
- Prednisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Prednisone Major
Other interactions of Deferasirox
Frequently asked questions
Can I take Deferasirox with Prednisone?
MediHelp rates the interaction as moderate. Deferasirox and Prednisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can injure the gastrointestinal mucosa, and deferasirox carries labeled warnings for GI hemorrhage and ulceration. Concurrent corticosteroid use may add to this risk, particularly in older patients or those with advanced disease and low platelets.
How serious is the interaction between Deferasirox and Prednisone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for GI symptoms and bleeding and consider gastroprotection in at-risk patients. Promptly evaluate any GI bleeding and interrupt deferasirox if it occurs.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Measles vaccine, Mifepristone. The full list is on the Prednisone page.
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