Drug interactions
Deferasirox + Quetiapine
Severity: Moderate
Deferasirox and Quetiapine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox can induce CYP3A4 and may lower quetiapine concentrations, potentially reducing antipsychotic effect. The magnitude is uncertain and probably modest.
What this interaction means in plain words
Deferasirox and Quetiapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deferasirox belongs to Miscellaneous; Quetiapine belongs to Central Nervous System.
Why it happens
Deferasirox induces CYP3A4, increasing quetiapine metabolism.
What to do
Monitor for reduced quetiapine response and increase the dose if clinically needed; reassess if deferasirox is stopped.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Quetiapine
- Adagrasib + Quetiapine Major
- Amiodarone + Quetiapine Major
- Amisulpride + Quetiapine Major
- Amoxapine + Quetiapine Major
- Anagrelide + Quetiapine Major
- Apalutamide + Quetiapine Major
Other interactions of Deferasirox
Frequently asked questions
Can I take Deferasirox with Quetiapine?
MediHelp rates the interaction as moderate. Deferasirox and Quetiapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deferasirox can induce CYP3A4 and may lower quetiapine concentrations, potentially reducing antipsychotic effect. The magnitude is uncertain and probably modest.
How serious is the interaction between Deferasirox and Quetiapine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for reduced quetiapine response and increase the dose if clinically needed; reassess if deferasirox is stopped.
What other medicines interact with Quetiapine?
MediHelp also lists interactions of Quetiapine with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Quetiapine page.
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