Drug reference
quetiapine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Anti Psychotic (atypical))
Mechanism of action
Atypical antipsychotic related to clozapine; reduces positive and negative symptoms of psychotic disorders via antagonism of multiple neurotransmitter receptors in brain, including dopamine D1 and D2, histamine H1, alpha1- and alpha2-adrenergic, and serotonin types 1 and 2 (5-HT1A, 5-HT2);
Common side effects
- Increased appetite
- Extrapyramidal symptoms
- Dizziness
- Fatigue
- Increased total cholesterol
- Increased diastolic blood pressure
- Increased triglycerides
Known interactions (7)
- amisulpride + quetiapine Major
- ketoconazole + quetiapine Major
- quetiapine + rifampin Major
- quetiapine + ritonavir Major
- cabergoline + quetiapine Moderate
- dopamine + quetiapine Moderate
- goserelin + quetiapine Moderate
Related conditions
Frequently asked questions
What drug class is quetiapine?
quetiapine belongs to: Central Nervous System.
How does quetiapine work?
Atypical antipsychotic related to clozapine; reduces positive and negative symptoms of psychotic disorders via antagonism of multiple neurotransmitter receptors in brain, including dopamine D1 and D2, histamine H1, alpha1- and alpha2-adrenergic, and serotonin types 1 and 2 (5-HT1A, 5-HT2);
What are the common side effects of quetiapine?
Increased appetite, Extrapyramidal symptoms, Dizziness, Fatigue, Increased total cholesterol, Increased diastolic blood pressure, Increased triglycerides
Which drugs interact with quetiapine?
amisulpride, ketoconazole, rifampin, ritonavir, cabergoline, dopamine, goserelin
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