Drug interactions
Deferasirox + Quinidine
Severity: Moderate
Deferasirox and Quinidine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox can induce CYP3A4 and may lower quinidine concentrations. Reduced antiarrhythmic effect is possible.
What this interaction means in plain words
Deferasirox and Quinidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deferasirox belongs to Miscellaneous; Quinidine belongs to Anti Parasitic.
Why it happens
Induction of CYP3A4-mediated quinidine metabolism by deferasirox.
What to do
Monitor quinidine levels and ECG when deferasirox is started or stopped, and adjust the quinidine dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Quinidine
- Adagrasib + Quinidine Contraindicated
- Arsenic trioxide + Quinidine Contraindicated
- Artemether / lumefantrine + Quinidine Contraindicated
- Chloroquine + Quinidine Contraindicated
- Dofetilide + Quinidine Contraindicated
- Dronedarone + Quinidine Contraindicated
Other interactions of Deferasirox
Frequently asked questions
Can I take Deferasirox with Quinidine?
MediHelp rates the interaction as moderate. Deferasirox and Quinidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deferasirox can induce CYP3A4 and may lower quinidine concentrations. Reduced antiarrhythmic effect is possible.
How serious is the interaction between Deferasirox and Quinidine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor quinidine levels and ECG when deferasirox is started or stopped, and adjust the quinidine dose.
What other medicines interact with Quinidine?
MediHelp also lists interactions of Quinidine with, for example, Adagrasib, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Quinidine page.
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