Drug interactions
Deferasirox + Sufentanil
Severity: Minor
Deferasirox and Sufentanil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox may reduce sufentanil exposure through CYP3A4 induction, potentially lessening analgesia. The effect is likely small and short-term sufentanil use limits relevance.
What this interaction means in plain words
Deferasirox and Sufentanil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Deferasirox belongs to Miscellaneous; Sufentanil belongs to Musculoskeletal.
Why it happens
Possible weak CYP3A4 induction by deferasirox increases sufentanil metabolism.
What to do
Titrate sufentanil to analgesic effect and respiratory status; no preemptive dose change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Deferasirox
Other interactions of Sufentanil
- Alprazolam + Sufentanil Major
- Amitriptyline + Sufentanil Major
- Amobarbital + Sufentanil Major
- Aripiprazole + Sufentanil Major
- Asenapine + Sufentanil Major
- Baclofen + Sufentanil Major
Frequently asked questions
Can I take Deferasirox with Sufentanil?
MediHelp rates the interaction as minor. Deferasirox and Sufentanil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Deferasirox may reduce sufentanil exposure through CYP3A4 induction, potentially lessening analgesia. The effect is likely small and short-term sufentanil use limits relevance.
How serious is the interaction between Deferasirox and Sufentanil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Titrate sufentanil to analgesic effect and respiratory status; no preemptive dose change is needed.
What other medicines interact with Deferasirox?
MediHelp also lists interactions of Deferasirox with, for example, Acetylsalicylic acid, Alosetron, Aluminum hydroxide. The full list is on the Deferasirox page.
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