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Drug interactions

Deferasirox + Vardenafil

Severity: Minor

Deferasirox and Vardenafil: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Deferasirox may induce CYP3A4 and slightly lower exposure to substrates such as vardenafil. Reduced effect is possible but uncommon.

What this interaction means in plain words

Deferasirox and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Deferasirox belongs to Miscellaneous; Vardenafil belongs to Genitourinary.

Evidence level: Low

Why it happens

Possible CYP3A4 induction increasing vardenafil metabolism.

What to do

Monitor erectile response and adjust vardenafil within labeled limits if effect is inadequate.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Deferasirox with Vardenafil?

MediHelp rates the interaction as minor. Deferasirox and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Deferasirox may induce CYP3A4 and slightly lower exposure to substrates such as vardenafil. Reduced effect is possible but uncommon.

How serious is the interaction between Deferasirox and Vardenafil?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor erectile response and adjust vardenafil within labeled limits if effect is inadequate.

What other medicines interact with Vardenafil?

MediHelp also lists interactions of Vardenafil with, for example, Amyl nitrite, Glyceryl trinitrate pr, Isosorbide dinitrate. The full list is on the Vardenafil page.

Full monographs, dosing and an interaction checker in the MediHelp app

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