Drug interactions
Deflazacort + Ublituximab
Severity: Moderate
Deflazacort and Ublituximab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ublituximab depletes B cells and deflazacort suppresses immune function, so the combination may increase the risk of infection. Corticosteroids are often given as premedication for infusions, but prolonged use adds to immunosuppression.
What this interaction means in plain words
Deflazacort and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deflazacort belongs to Miscellaneous; Ublituximab belongs to Miscellaneous.
Why it happens
Additive immunosuppression from B-cell depletion and glucocorticoid effects.
What to do
Monitor for infections and review the need for continued corticosteroid. Check vaccination status and screen for hepatitis B before ublituximab.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Other interactions of Ublituximab
Frequently asked questions
Can I take Deflazacort with Ublituximab?
MediHelp rates the interaction as moderate. Deflazacort and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ublituximab depletes B cells and deflazacort suppresses immune function, so the combination may increase the risk of infection. Corticosteroids are often given as premedication for infusions, but prolonged use adds to immunosuppression.
How serious is the interaction between Deflazacort and Ublituximab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for infections and review the need for continued corticosteroid. Check vaccination status and screen for hepatitis B before ublituximab.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
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