Drug interactions
Delavirdine + Terbinafine
Severity: Minor
Delavirdine and Terbinafine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Delavirdine inhibits several CYP enzymes and might raise terbinafine concentrations. The clinical effect is probably limited given terbinafine's multiple clearance pathways.
What this interaction means in plain words
Delavirdine and Terbinafine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Delavirdine inhibits CYP3A4 and CYP2C9, which contribute to terbinafine metabolism.
What to do
No dose change is generally needed. Monitor for terbinafine adverse effects such as hepatic enzyme elevation.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Terbinafine
- Terbinafine + Thioridazine Contraindicated
- Desipramine + Terbinafine Major
- Eliglustat + Terbinafine Major
- Flecainide + Terbinafine Major
- Imipramine + Terbinafine Major
- Maprotiline + Terbinafine Major
Frequently asked questions
Can I take Delavirdine with Terbinafine?
MediHelp rates the interaction as minor. Delavirdine and Terbinafine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Delavirdine inhibits several CYP enzymes and might raise terbinafine concentrations. The clinical effect is probably limited given terbinafine's multiple clearance pathways.
How serious is the interaction between Delavirdine and Terbinafine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is generally needed. Monitor for terbinafine adverse effects such as hepatic enzyme elevation.
What other medicines interact with Terbinafine?
MediHelp also lists interactions of Terbinafine with, for example, Thioridazine, Desipramine, Eliglustat. The full list is on the Terbinafine page.
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