Drug interactions
Deoxycholic acid + Warfarin
Severity: Minor
Deoxycholic acid and Warfarin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deoxycholic acid is injected subcutaneously for submental fat and is associated with bruising and hematoma at the site. Systemic exposure is minimal, and no established pharmacokinetic interaction with warfarin exists, though local bleeding may be more prominent.
What this interaction means in plain words
Deoxycholic acid and Warfarin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Deoxycholic acid belongs to Miscellaneous; Warfarin belongs to Cardiovascular.
Why it happens
No systemic mechanism is established; the concern is additive local bruising and bleeding at injection sites.
What to do
Be aware of the increased risk of injection-site bruising and check INR is in range before treatment. No routine dose change is required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Warfarin
- Defibrotide + Warfarin Contraindicated
- Ketorolac + Warfarin Contraindicated
- Abciximab + Warfarin Major
- Acetylsalicylic acid + Warfarin Major
- Adagrasib + Warfarin Major
- Amiodarone + Warfarin Major
Frequently asked questions
Can I take Deoxycholic acid with Warfarin?
MediHelp rates the interaction as minor. Deoxycholic acid and Warfarin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Deoxycholic acid is injected subcutaneously for submental fat and is associated with bruising and hematoma at the site. Systemic exposure is minimal, and no established pharmacokinetic interaction with warfarin exists, though local bleeding may be more prominent.
How serious is the interaction between Deoxycholic acid and Warfarin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Be aware of the increased risk of injection-site bruising and check INR is in range before treatment. No routine dose change is required.
What other medicines interact with Warfarin?
MediHelp also lists interactions of Warfarin with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Warfarin page.
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