Drug interactions
Deutetrabenazine + Lamotrigine
Severity: Minor
Deutetrabenazine and Lamotrigine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deutetrabenazine commonly causes somnolence, and lamotrigine can cause drowsiness and dizziness. Together they may increase sedation and impair alertness.
What this interaction means in plain words
Deutetrabenazine and Lamotrigine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Deutetrabenazine belongs to Central Nervous System; Lamotrigine belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects.
What to do
Counsel about sedation and driving. Reduce the dose of one agent if drowsiness is troublesome.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lamotrigine
Other interactions of Deutetrabenazine
- Deutetrabenazine + Isocarboxazid Contraindicated
- Deutetrabenazine + Linezolid Contraindicated
- Deutetrabenazine + Phenelzine Contraindicated
- Deutetrabenazine + Rasagiline Contraindicated
- Deutetrabenazine + Safinamide Contraindicated
- Deutetrabenazine + Selegiline Contraindicated
Frequently asked questions
Can I take Deutetrabenazine with Lamotrigine?
MediHelp rates the interaction as minor. Deutetrabenazine and Lamotrigine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Deutetrabenazine commonly causes somnolence, and lamotrigine can cause drowsiness and dizziness. Together they may increase sedation and impair alertness.
How serious is the interaction between Deutetrabenazine and Lamotrigine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel about sedation and driving. Reduce the dose of one agent if drowsiness is troublesome.
What other medicines interact with Lamotrigine?
MediHelp also lists interactions of Lamotrigine with, for example, Desogestrel-ethinyl estradiol, Divalproex, Dofetilide. The full list is on the Lamotrigine page.
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