Drug interactions
Devil's claw + Diclofenac
Severity: Minor
Devil's claw and Diclofenac: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Devil's claw is used for joint pain and may have mild antiplatelet effects. Taken with diclofenac it duplicates therapy and may add to bleeding or GI irritation, though documentation is limited.
What this interaction means in plain words
Devil's claw and Diclofenac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive antiplatelet effect; mechanism not firmly established.
What to do
Avoid combining the two for the same indication and monitor for bleeding or gastric symptoms if both are used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Diclofenac
- Diclofenac + Ketorolac Contraindicated
- Diclofenac + Ketorolac intranasal Contraindicated
- Aceclofenac + Diclofenac Major
- Acemetacin + Diclofenac Major
- Alteplase + Diclofenac Major
- Amiloride + Diclofenac Major
Frequently asked questions
Can I take Devil's claw with Diclofenac?
MediHelp rates the interaction as minor. Devil's claw and Diclofenac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Devil's claw is used for joint pain and may have mild antiplatelet effects. Taken with diclofenac it duplicates therapy and may add to bleeding or GI irritation, though documentation is limited.
How serious is the interaction between Devil's claw and Diclofenac?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining the two for the same indication and monitor for bleeding or gastric symptoms if both are used.
What other medicines interact with Diclofenac?
MediHelp also lists interactions of Diclofenac with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Diclofenac page.
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