Drug interactions
Devil's claw + Oxaprozin
Severity: Minor
Devil's claw and Oxaprozin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Devil's claw has been reported to have antiplatelet effects and is itself used for pain, so it may add to NSAID bleeding risk and GI irritation. The clinical evidence is limited.
What this interaction means in plain words
Devil's claw and Oxaprozin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive antiplatelet effect; the mechanism of devil's claw on coagulation is not well established.
What to do
Avoid unnecessary combined use; if both are taken, counsel on signs of GI bleeding and bruising.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Oxaprozin
- Ketorolac intranasal + Oxaprozin Contraindicated
- Ketorolac + Oxaprozin Contraindicated
- Aceclofenac + Oxaprozin Major
- Acemetacin + Oxaprozin Major
- Acetylsalicylic acid + Oxaprozin Major
- Alteplase + Oxaprozin Major
Frequently asked questions
Can I take Devil's claw with Oxaprozin?
MediHelp rates the interaction as minor. Devil's claw and Oxaprozin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Devil's claw has been reported to have antiplatelet effects and is itself used for pain, so it may add to NSAID bleeding risk and GI irritation. The clinical evidence is limited.
How serious is the interaction between Devil's claw and Oxaprozin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unnecessary combined use; if both are taken, counsel on signs of GI bleeding and bruising.
What other medicines interact with Oxaprozin?
MediHelp also lists interactions of Oxaprozin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Oxaprozin page.
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