Drug interactions
Dexamethasone + Erdafitinib
Severity: Minor
Dexamethasone and Erdafitinib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Erdafitinib inhibits P-glycoprotein and may modestly raise dexamethasone exposure. Clinically significant effects are unlikely given dexamethasone's wide therapeutic margin.
What this interaction means in plain words
Dexamethasone and Erdafitinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dexamethasone belongs to Endocrine; Erdafitinib belongs to Oncology.
Why it happens
Erdafitinib inhibits P-glycoprotein efflux of dexamethasone.
What to do
No routine action; monitor for corticosteroid adverse effects such as hyperglycemia during prolonged therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dexamethasone
- Bcg vaccine live + Dexamethasone Contraindicated
- Dexamethasone + Mifepristone Contraindicated
- Dexamethasone + Rilpivirine Contraindicated
- Dexamethasone + Smallpox vaccine live Contraindicated
- Dexamethasone + Varicella virus vaccine live Contraindicated
- Dexamethasone + Yellow fever vaccine Contraindicated
Other interactions of Erdafitinib
Frequently asked questions
Can I take Dexamethasone with Erdafitinib?
MediHelp rates the interaction as minor. Dexamethasone and Erdafitinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Erdafitinib inhibits P-glycoprotein and may modestly raise dexamethasone exposure. Clinically significant effects are unlikely given dexamethasone's wide therapeutic margin.
How serious is the interaction between Dexamethasone and Erdafitinib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action; monitor for corticosteroid adverse effects such as hyperglycemia during prolonged therapy.
What other medicines interact with Dexamethasone?
MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.
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