Drug interactions
Dexamethasone + Ublituximab
Severity: Moderate
Dexamethasone and Ublituximab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ublituximab depletes B cells and dexamethasone suppresses immunity, so together they may raise infection risk. Dexamethasone is also commonly used as infusion premedication, which is accepted practice.
What this interaction means in plain words
Dexamethasone and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dexamethasone belongs to Endocrine; Ublituximab belongs to Miscellaneous.
Why it happens
Additive immunosuppression from B-cell depletion and glucocorticoid effects.
What to do
Limit steroid use to premedication doses where possible, and monitor for infection. Avoid prolonged high-dose courses when feasible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dexamethasone
- Bcg vaccine live + Dexamethasone Contraindicated
- Dexamethasone + Mifepristone Contraindicated
- Dexamethasone + Rilpivirine Contraindicated
- Dexamethasone + Smallpox vaccine live Contraindicated
- Dexamethasone + Varicella virus vaccine live Contraindicated
- Dexamethasone + Yellow fever vaccine Contraindicated
Other interactions of Ublituximab
Frequently asked questions
Can I take Dexamethasone with Ublituximab?
MediHelp rates the interaction as moderate. Dexamethasone and Ublituximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ublituximab depletes B cells and dexamethasone suppresses immunity, so together they may raise infection risk. Dexamethasone is also commonly used as infusion premedication, which is accepted practice.
How serious is the interaction between Dexamethasone and Ublituximab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Limit steroid use to premedication doses where possible, and monitor for infection. Avoid prolonged high-dose courses when feasible.
What other medicines interact with Dexamethasone?
MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.
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