Drug interactions
Dexamethasone-tobramycin + Vardenafil
Severity: Minor
Dexamethasone-tobramycin and Vardenafil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dexamethasone may reduce vardenafil exposure via CYP3A4 induction, possibly reducing its effect. Clinical significance is likely small.
What this interaction means in plain words
Dexamethasone-tobramycin and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dexamethasone-tobramycin belongs to Anti Bacterial; Vardenafil belongs to Genitourinary.
Why it happens
Dexamethasone induces CYP3A4, increasing vardenafil metabolism.
What to do
Monitor erectile response and adjust vardenafil dose if needed during prolonged dexamethasone use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dexamethasone-tobramycin
Other interactions of Vardenafil
- Amyl nitrite + Vardenafil Contraindicated
- Glyceryl trinitrate pr + Vardenafil Contraindicated
- Isosorbide dinitrate + Vardenafil Contraindicated
- Isosorbide mononitrate + Vardenafil Contraindicated
- Nicorandil + Vardenafil Contraindicated
- Nitroglycerin po + Vardenafil Contraindicated
Frequently asked questions
Can I take Dexamethasone-tobramycin with Vardenafil?
MediHelp rates the interaction as minor. Dexamethasone-tobramycin and Vardenafil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dexamethasone may reduce vardenafil exposure via CYP3A4 induction, possibly reducing its effect. Clinical significance is likely small.
How serious is the interaction between Dexamethasone-tobramycin and Vardenafil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor erectile response and adjust vardenafil dose if needed during prolonged dexamethasone use.
What other medicines interact with Dexamethasone-tobramycin?
MediHelp also lists interactions of Dexamethasone-tobramycin with, for example, Capreomycin, Carboplatin, Ciprofloxacin. The full list is on the Dexamethasone-tobramycin page.
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