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Drug interactions

Dexfenfluramine + Formoterol-mometasone

Severity: Moderate

Dexfenfluramine and Formoterol-mometasone: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Dexfenfluramine has serotonergic and some sympathomimetic activity, and formoterol is a beta-2 agonist that can increase heart rate and blood pressure. Combined use may add to cardiovascular stimulation. Dexfenfluramine has been withdrawn in most markets, limiting relevance.

What this interaction means in plain words

Dexfenfluramine and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive sympathomimetic cardiovascular effects.

What to do

Monitor heart rate and blood pressure, and review the need for the anorectic agent in patients with cardiovascular disease.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Dexfenfluramine with Formoterol-mometasone?

MediHelp rates the interaction as moderate. Dexfenfluramine and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dexfenfluramine has serotonergic and some sympathomimetic activity, and formoterol is a beta-2 agonist that can increase heart rate and blood pressure. Combined use may add to cardiovascular stimulation. Dexfenfluramine has been withdrawn in most markets, limiting relevance.

How serious is the interaction between Dexfenfluramine and Formoterol-mometasone?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure, and review the need for the anorectic agent in patients with cardiovascular disease.

What other medicines interact with Formoterol-mometasone?

MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.

Full monographs, dosing and an interaction checker in the MediHelp app

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