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Drug interactions

Dexfenfluramine + Ipratropium-salbutamol

Severity: Moderate

Dexfenfluramine and Ipratropium-salbutamol: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Dexfenfluramine is a serotonergic anorectic, now withdrawn in most markets, with limited sympathomimetic activity. Combination with salbutamol may add modestly to heart rate or blood pressure effects.

What this interaction means in plain words

Dexfenfluramine and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Possible additive sympathomimetic effects on heart rate and blood pressure.

What to do

Monitor blood pressure and heart rate; use of dexfenfluramine is rarely relevant today because it is withdrawn.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Dexfenfluramine with Ipratropium-salbutamol?

MediHelp rates the interaction as moderate. Dexfenfluramine and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dexfenfluramine is a serotonergic anorectic, now withdrawn in most markets, with limited sympathomimetic activity. Combination with salbutamol may add modestly to heart rate or blood pressure effects.

How serious is the interaction between Dexfenfluramine and Ipratropium-salbutamol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate; use of dexfenfluramine is rarely relevant today because it is withdrawn.

What other medicines interact with Ipratropium-salbutamol?

MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.

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