Drug interactions
Dexfenfluramine + Quetiapine
Severity: Minor
Dexfenfluramine and Quetiapine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dexfenfluramine is a serotonergic anorectic that is no longer marketed. Its interaction with quetiapine is not well characterized, and the net effect on sedation is unclear.
What this interaction means in plain words
Dexfenfluramine and Quetiapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Not established; possible opposing central serotonergic and sedative effects.
What to do
No specific action is needed beyond monitoring for sedation and mental status changes. Dexfenfluramine is withdrawn in most markets.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quetiapine
- Adagrasib + Quetiapine Major
- Amiodarone + Quetiapine Major
- Amisulpride + Quetiapine Major
- Amoxapine + Quetiapine Major
- Anagrelide + Quetiapine Major
- Apalutamide + Quetiapine Major
Frequently asked questions
Can I take Dexfenfluramine with Quetiapine?
MediHelp rates the interaction as minor. Dexfenfluramine and Quetiapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dexfenfluramine is a serotonergic anorectic that is no longer marketed. Its interaction with quetiapine is not well characterized, and the net effect on sedation is unclear.
How serious is the interaction between Dexfenfluramine and Quetiapine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed beyond monitoring for sedation and mental status changes. Dexfenfluramine is withdrawn in most markets.
What other medicines interact with Quetiapine?
MediHelp also lists interactions of Quetiapine with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Quetiapine page.
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